One of my all-time favorite novels is Hemingway's The Sun Also Rises. But one of the main characters of the novel, Robert Cohn, is built around an antisemitic stereotype, and most of the other characters indulge in antisemitic assaults against Cohn. (Hollywood's version politely excised most of the antisemitic references.) For a cataloguing of the antisemitic instances, see this website (it's not comprehensive, but it at least gives an overview).
Is it accurate to call this novel "antisemitic"? I really don't have a firm answer.
It seems to me that the antisemitism of the novel is more than just incidental. In other words, I think the story depends on the antisemitic tropes and that the characters' antisemitism is integral to who they are. The story wouldn't be the same story without the antisemitism. (In contrast, there is a little bit of anti-black racism as well. The narrator and main character, Jake Barnes, uses the "n" word several times to describe black people. In my view, those instances could probably be excised from the book without changing the main flow of the story while excising all the antisemitic references would substantially change the story.)
One of the arguments against calling the novel antisemitic--and an argument which I've read somewhere, but cannot right now find the citation for--is that Hemingway was merely detailing a group of wasp-ish people for whom antisemitism was a matter of course. By this argument, the antisemitism of the novel would be comparable to the racism in any novel about racists. If an author's characters are racist, he or she has to portray them saying racist things. And, of course, The Sun Also Rises is written in the first person, so it's hard, if not impossible to tease the racism of the narrator (Jake Barnes) from the racist message, if any, of the novel.
Still, I have a sneaking suspicion that the antisemitism in the novel is more than just a character representation. I, however, cannot put my finger on it.